The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma
نویسندگان
چکیده
The secretion of interleukin-10 by both malignant and immune cells promotes the progression of lung tumors, hence negatively impacting on patient prognosis. As interleukin-10 mediates oncogenic effects through the PI3K/AKT signaling pathway, PI3K/AKT inhibitors might sensitize cancer cells to chemotherapy, thus favoring tumor regression and improving disease outcome.
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2013